desvenlafaxine will increase the amount or influence of codeine by influencing hepatic enzyme CYP2D6 metabolism. Use Caution/Keep an eye on. Desvenlafaxine inhibits CYP2D6; with bigger desvenlafaxine doses (ie, 400 mg) minimize the CYP2D6 substrate dose by around fifty%; no dosage adjustment required with desvenlafaxine doses 7 consecutive days pro… Read More